Details

Autor(en) / Beteiligte

• Ojika, Makoto
• Molli, Shylaja D
• Kanazawa, Harumi
• Yajima, Arata
• Toda, Kou
• Nukada, Tomoo
• Mao, Haimeng
• Murata, Ryo
• Asano, Tomoyo
• Qi, Jianhua
• Sakagami, Youji

Titel

The second Phytophthora mating hormone defines interspecies biosynthetic crosstalk

Ist Teil von

• Nature chemical biology, 2011-07, Vol.7 (9), p.591-593

Ort / Verlag

United States

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• The heterothallic species of the agricultural pest Phytophthora use mating hormones α1 and α2 to regulate their sexual reproduction. Here we describe the absolute stereostructure of the second mating hormone α2 as defined by spectroscopic analysis and total synthesis. We have uncovered not only the interspecies universality of α hormones but also the pathway by which α2 is biosynthesized from phytol by A2-mating type strains and metabolized to α1 by A1 strains.