The American surgeon, 1990-07, Vol.56 (7), p.428
1990
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Details
- Autor(en) / Beteiligte
- Titel
- Alternatives in the surgical management of in situ breast cancer. A meta-analysis of outcome
- Ist Teil von
- The American surgeon, 1990-07, Vol.56 (7), p.428
- Ort / Verlag
- United States
- Erscheinungsjahr
- 1990
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The surgical management of lobular carcinoma in situ (LCIS) and ductal carcinoma in situ (DCIS) remains controversial. For in situ breast cancer local excision (LE), local excision and radiation therapy (LERT) and mastectomy (MAST) have all been advocated. A search of the English literature found 13 reports concerning the surgical management of LCIS and 12 reports concerning the management of DCIS. The data were combined in a meta-analysis of outcome. As expected, recurrence rates following LE with both LCIS 8.4%) and DCIS (17%) are high. However,the overall mortality following mastectomy for recurrence, LCIS (2.8%) and DCIS (2.3%) does not differ statistically from those treated initially with mastectomy for LCIS (0.9%) and DCIS (1.7%). We conclude from these data that local recurrence after breast conserving procedures for in situ breast cancer does not carry an ominous prognosis. This knowledge should aid in planning individual therapy.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0003-1348Titel-ID: cdi_pubmed_primary_2164336
- Format
- –
- Schlagworte
- Breast Neoplasms - mortality, Breast Neoplasms - radiotherapy, Breast Neoplasms - surgery, Carcinoma - mortality, Carcinoma - radiotherapy, Carcinoma - surgery, Carcinoma in Situ - mortality, Carcinoma in Situ - radiotherapy, Carcinoma in Situ - surgery, Carcinoma, Intraductal, Noninfiltrating - mortality, Carcinoma, Intraductal, Noninfiltrating - radiotherapy, Carcinoma, Intraductal, Noninfiltrating - surgery, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Mastectomy - methods, Meta-Analysis as Topic, Neoplasm Recurrence, Local, Survival Rate