Yao hsüeh hsüeh pao, 2010-03, Vol.45 (3), p.283
2010
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Details
- Autor(en) / Beteiligte
- Titel
- Advances in the study of the anti-tumor activity of small molecule vascular disrupting agents
- Ist Teil von
- Yao hsüeh hsüeh pao, 2010-03, Vol.45 (3), p.283
- Ort / Verlag
- China
- Erscheinungsjahr
- 2010
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Vascular disrupting agents (VDAs) have presented a new kind of anti-cancer drug in recent years. VDAs take advantage of the weakness of established tumor endothelial cells and their supporting structures. In contrast to anti-angiogenic therapy, which inhibits the outgrowth of new blood vessels, vascular targeting treatments selectively attack the existing tumor vasculature. Here we summarized the anti-tumor activities, mechanisms and clinical applications of small molecule VDAs.
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 0513-4870Titel-ID: cdi_pubmed_primary_21351502
- Format
- –
- Schlagworte
- Angiogenesis Inhibitors - chemistry, Angiogenesis Inhibitors - pharmacology, Angiogenesis Inhibitors - therapeutic use, Animals, Antineoplastic Agents - chemistry, Antineoplastic Agents - pharmacology, Antineoplastic Agents - therapeutic use, Bibenzyls - chemistry, Bibenzyls - pharmacology, Bibenzyls - therapeutic use, Diphosphates - chemistry, Diphosphates - pharmacology, Diphosphates - therapeutic use, Endothelial Cells - drug effects, Humans, Molecular Structure, Neoplasms - drug therapy, Neoplasms - pathology, Neovascularization, Pathologic, Oligopeptides - chemistry, Oligopeptides - pharmacology, Oligopeptides - therapeutic use, Organophosphorus Compounds - chemistry, Organophosphorus Compounds - pharmacology, Organophosphorus Compounds - therapeutic use, Serine - analogs & derivatives, Serine - chemistry, Serine - pharmacology, Serine - therapeutic use, Stilbenes - chemistry, Stilbenes - pharmacology, Stilbenes - therapeutic use, Tubulin Modulators - chemistry, Tubulin Modulators - pharmacology, Tubulin Modulators - therapeutic use, Xanthones - chemistry, Xanthones - pharmacology, Xanthones - therapeutic use