Details

Autor(en) / Beteiligte

• Ege, Markus J
• Mayer, Melanie
• Normand, Anne-Cécile
• Genuneit, Jon
• Cookson, William O.C.M
• Braun-Fahrländer, Charlotte
• Heederik, Dick
• Piarroux, Renaud
• von Mutius, Erika

Titel

Exposure to Environmental Microorganisms and Childhood Asthma

Ist Teil von

• The New England journal of medicine, 2011-02, Vol.364 (8), p.701-709

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2011

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Growing up on a farm protects children from asthma. In this study, the investigators show that the diversity of microbial exposure of farm children as compared with children in the reference group can explain the observed protective effect. Environmental exposure to microorganisms has repeatedly been found to be inversely related to the manifestation of atopic diseases such as asthma and hay fever. This observation has been made in various contexts, including the studies conducted in the Republic of Karelia (Russia) and North Karelia (Finland), in which two populations in geographically adjacent areas live under different environmental conditions. In the population with higher bacterial exposures, the prevalence of asthma and atopy was substantially lower. 1 Another example supporting this notion is the lower prevalence of asthma and atopy among children raised on a farm. 2 Many studies using microbial products, such . . .