Details

Autor(en) / Beteiligte

• Lu, Xiao-guang
• Zhan, Li-bin
• Kang, Xin
• Liu, Li
• Li, Yuan-zhong
• Yu, Jian
• Fan, Zhi-wei
• Bai, Li-zhi
• Ji, Chun-yang
• Wang, Xiao-zhou

Titel

Clinical research of Dahuang Fuzi decoction in auxiliary treatment of severe acute pancreatitis: a multi-center observation in 206 patients

Ist Teil von

• Zhongguo wei zhong bing ji jiu yi xue, 2010-12, Vol.22 (12), p.723

Ort / Verlag

China

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• To observe the efficacy of Dahuang Fuzi decoction in patients with severe acute pancreatitis (SAP), and to provide valuable medical evidences for a treatment of SAP with combined traditional Chinese and western medicine. A prospective, multi-center, randomized, controlled clinical trial was designed. Two hundred and six adult patients with SAP admitted to intensive care unit (ICU) in three tertiary university teaching hospitals in Dalian from January 2007 to February 2010 were randomly divided into two groups: soapsuds enema control group (control group, n=101) and Dahuang Fuzi decoction enema study group (study group, n=105). The levels of serum amylase, albumin (Alb), D-lactic acid, endotoxin and diamine oxidase (DAO), high-sensitive C-reactive protein (hs-CRP), immunoglobulin (IgG, IgA, IgM), complements (C3, C4), tumour necrosis factor-α (TNF-α), interleukins (IL-6, IL-8) were determined before and after treatment for 2, 4, 7 days. The bowel sound, gastrointestinal function score, the acute physiology and