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Details

Autor(en) / Beteiligte
Titel
A reinforcement of acupuncture on the cardiac effect of dobatamine: exhibition of acupoint's functional specificity
Ist Teil von
  • Zhēncì yánjiū, 2010-06, Vol.35 (3), p.188
Ort / Verlag
China
Erscheinungsjahr
2010
Quelle
MEDLINE
Beschreibungen/Notizen
  • To investigate the functional specificity of acupoint by means of acupoint injection of Dobutamine Hydrochloride (DH). Male SD rats were randomized into normal control (NC), EA-Neiguan (PC6) + acupoint injection (AI, EA-PC 6 + AI), EA-Zusanli (ST 36) + AI (EA-ST 36 + AI), and EA-intramuscular injection site (IMIS) + intramuscular injection (EA-IMIS+ IMI) groups,with 8 rats being in each group. EA (2 Hz/15 Hz, 3 mA) was applied to bilateral "Neiguan" (PC 6), "Zusanli "(ST 36) and muscular-injection site for 10 min. DH (a beta1-adrenoceptor agonist) solution (100 microg/kg) was injected intramuscularly into the gluteus maximus after termination of EA intervention. The left ventricular systolic pressure (LVSP), heart rate (HR) and + dp/dt max were recorded before and 2, 5, 15 and 30 min after injection of DH. The values of LVSP, HR and + dp/dt max in EA-PC 6 + AI group were significantly higher than those in NC, EA-ST 36 + AI, and EA-IMIS + IMI groups (P < 0.01) 2 and 5 minutes after EA plus acupoint injection o

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