Details

Autor(en) / Beteiligte

• Yeh, Chih-Ko
• Christodoulides, Nicolaos J
• Floriano, Pierre N
• Miller, Craig S
• Ebersole, Jeffrey L
• Weigum, Shannon E
• McDevitt, John
• Redding, Spencer W

Titel

Current development of saliva/oral fluid-based diagnostics

Ist Teil von

• Texas dental journal, 2010-07, Vol.127 (7), p.651

Ort / Verlag

United States

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• Saliva can be easily obtained in medical and non-medical settings, and contains numerous bio-molecules, including those typically found in serum for disease detection and monitoring. In the past two decades, the achievements of high-throughput approaches afforded by biotechnology and nanotechnology allow for disease-specific salivary biomarker discovery and establishment of rapid, multiplex, and miniaturized analytical assays. These developments have dramatically advanced saliva-based diagnostics. In this review, we discuss the current consensus on development of saliva/oral fluid-based diagnostics and provide a summary of recent research advancements of the Texas-Kentucky Saliva Diagnostics Consortium. In the foreseeable future, current research on saliva based diagnostic methods could revolutionize health care.