Details

Autor(en) / Beteiligte

• Xu, D-X
• Vachon, M
• Densmore, A
• Ma, R
• Delâge, A
• Janz, S
• Lapointe, J
• Li, Y
• Lopinski, G
• Zhang, D
• Liu, Q Y
• Cheben, P
• Schmid, J H

Titel

Label-free biosensor array based on silicon-on-insulator ring resonators addressed using a WDM approach

Ist Teil von

• Optics letters, 2010-08, Vol.35 (16), p.2771

Ort / Verlag

United States

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• We report a silicon-on-insulator ring resonator biosensor array with one output port, using wavelength division multiplexing as the addressing scheme. With the use of on-chip referencing for environmental drift cancellation, simultaneous monitoring of multiplexed molecular bindings is demonstrated, with a resolution of 0.3 pg/mm(2) (40 ag of total mass) for protein concentrations over 4 orders of magnitude down to 20 pM. Reactions are measured over time periods as long as 3 h with high stability.