Details

Autor(en) / Beteiligte

• Chen, Ang
• Xia, Ying-hua
• Chen, Wen
• Ling, Li
• Tan, Wen-kang
• Zheng, Rong-jia

Titel

Predictors of retention related factors at the initial methadone maintenance treatment clinics in Guangdong province

Ist Teil von

• Zhōnghuá liúxíngbìng zázhì, 2009-12, Vol.30 (12), p.1230

Ort / Verlag

China

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• To identify predictors of treatment retention problems at the two initial methadone maintenance treatment (MMT) clinics in Guangdong province, and to provide reference in reducing the rate of drop-outs. All of the patients were investigated at baseline and followed during the treatment period. Kaplan-Meier method on Survival Analysis was used to analyze retention related factors and predictors. 509 subjects were recruited in this study with median of retention time as 108 days (95%CI: 74 - 142 days). The retention rate at 1-, 3-, 6-, 12-months were 75.9%, 52.7%, 41.6%, 30.1%, respectively. Data from Multivariate Cox Proportional Hazard Model analysis showed predictors of retention would involve factors as HIV infection state at baseline (HR = 1.241, P = 0.047), daily methadone dose (HR = 0.633, P = 0.004) and secretly using drugs during treatment period (HR = 5.345, P = 0.000). The retention rates at the two initial MMT clinics in Guangdong province were low. Patients who were HIV negative at baseline but sti