Details

Autor(en) / Beteiligte

• Dardas, Petros
• Mezilis, Nikos
• Ninios, Vlasis
• Efthimiadis, Georgios K
• Tsikaderis, Dimitrios
• Pagourelias, Efstathios
• Pliakos, Christodoulos

Titel

Rheolytic thrombectomy in patients with acute coronary syndrome and large thrombus burden: initial and mid-term results from a single centre experience

Ist Teil von

• Hellenic journal of cardiology, 2010-01, Vol.51 (1), p.27

Ort / Verlag

Netherlands

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• The presence of a large intracoronary thrombus burden is a major complicating factor during percutaneous coronary intervention (PCI) in patients with an acute coronary syndrome (ACS). The use of rheolytic thrombectomy (RT) has been proposed to prevent thrombus-related complications, with conflicting results. The purpose of this study was to identify the feasibility and safety of this approach. We conducted a single-centre, retrospective, observational case-control study, comparing the outcomes of PCI in 26 consecutive patients with ACS and a large thrombus burden who underwent RT to those of a control group of 26 patients, matched with regard to artery location and initial TIMI flow grade. Despite the higher prevalence of acute ST-elevation myocardial infarction and the larger thrombus burden in the RT group, there was less incidence of distal embolisation/no-reflow and less use of vasoactive intracoronary agents. The final TIMI flow was identical in both groups. There was no difference between the two groups in the in-hospital and mid-term incidence of major adverse coronary events. In this study, the use of RT in patients with a large thrombus burden during acute PCI was both feasible and safe and reduced the incidence of initial no-reflow phenomenon.