Details

Autor(en) / Beteiligte

• Al-Jefri, A.
• Ayas, A.
• Al Musa, A.
• Al Mahr, M.
• Al Saleh, M.
• Rifai, S.
• Sabbah, R.
• Al Seraihy, A.
• Al Ahmari, A.
• Khairy, E.
• Al Hassan, I.
• El Solh, H.

Titel

Allogeneic Stem Cell Transplantation in Patients with β-thalassemia: King Faisal Specialist Hospital and Research Centre Experience

Ist Teil von

• Hemoglobin, 2009, Vol.33 (S1), p.S183-S187

Ort / Verlag

England: Informa UK Ltd

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• From January 1998-July 2006, 62 stem cell transplantation (SCT) were performed on 60 patients with β-thalassemia from HLA-related match donors. The overall survival (OS) and event free survival (EFS) for all patients were 94 and 77%. The outcome of allogeneic SCT in our experience is satisfactory with OS 92% and EFS 77%. Transplantation at a young age and when the disease is mild offers the best outcome. More advanced disease is associated with higher rate of rejection and severe graft versus host disease.