Details

Autor(en) / Beteiligte

• Cui, Na
• Yang, Yuan-hua
• Xie, Wan-mu
• Ma, Zhan-hong
• Luo, Ling
• Wang, Chen

Titel

The oxygen kinetic effect of inhaled iloprost in pulmonary artery hypertension and chronic thromboembolic pulmonary hypertension

Ist Teil von

• Zhonghua jiehe he huxi zazhi, 2009-07, Vol.32 (7), p.522

Ort / Verlag

China

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• To study the acute oxygen kinetic effect of inhaled iloprost in pulmonary artery hypertension and chronic thromboembolic pulmonary hypertension. Twenty-two and 24 patients who were admitted to our hospital between June 2006 and January 2009 with confirmed diagnosis of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) respectively were enrolled to this study. During right heart catheterization, the hemodynamics and oxygen kinetics were monitored at baseline and after inhaling Iloprost (20 micrograms). At baseline, the arterial partial pressure of oxygen (PaO2) was (63 +/- 10) mm Hg (1 mm Hg = 0.133 kPa) and (59 +/- 10) mm Hg respectively in PAH and CTEPH patients, and the oxygen delivery index (DO2I) and oxygen consumption index (VO2I) were (458 +/- 136) ml x min(-1) x m(-2) and (135 +/- 53) ml x min(-1) x m(-2) in PAH patients respectively, and (386 +/- 92) ml x min(-1) x m(-2) and (131 +/- 43) ml x min(-1) x m(-2) in CTEPH patients respectively. Three minutes aft