Details

Autor(en) / Beteiligte

• Hamaguchi, Reo
• Saito, Hiroaki
• Kegasawa, Kyoko
• Nakagawa, Atsushi
• Ryujin, Yasushi
• Noguchi, Saiko
• Sugimoto, Hideyasu
• Kobayashi, Akiko
• Yamazaki, Keiichi
• Jin, Yasuto
• Yoshimura, Nobuyuki
• Tsurikisawa, Naomi
• Akiyama, Kazuo

Titel

A case of hypersensitivity pneumonitis resulting from inhalation of Aspergillus niger in a greenhouse worker who raised roses

Ist Teil von

• Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2009-03, Vol.47 (3), p.205

Ort / Verlag

Japan

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• A 57-year-old woman was referred because of exertional dyspnea, fever, and cough in June 2006. She had been employed to culture roses in greenhouses since 1991 and had developed a cough during the summer from 2003. Chest CT scan revealed diffuse centrilobular micronodules. Transbronchial lung biopsy specimens demonstrated alveolitis with lymphocytes and non-necrotizing epithelioid cell granulomas. After admission, both the patient's symptoms and laboratory data improved without medication. However, upon her return to work in the greenhouse, cough and exertional dyspnea reappeared. Aspergillus niger was detected in the greenhouse. Her serum was assayed for precipitating antibodies against various antigens, and precipitating antibodies against Aspergillus fumigatus, Aspergillus flavus, Aspergillus glaucus, and Aspergillus niger were demonstrated. In a double immunodiffusion test, cross-reactivity between Aspergillus niger and other Aspergillus species was indicated. Consequently, she was diagnosed as having hypersensitivity pneumonitis resulting from the inhalation of Aspergillus niger.