Details

Autor(en) / Beteiligte

• Wang, Qing-guang
• Lu, Lian-fang
• Zhou, Yan-bing
• Cao, Shou-gen
• Wang, Dong-sheng
• Lv, Liang

Titel

Effects of intensive insulin therapy on insulin resistance and serum proteins after radical gastrectomy

Ist Teil von

• Zhonghua wei chang wai ke za zhi, 2008-09, Vol.11 (5), p.444

Ort / Verlag

China

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the effects of intensive insulin therapy on insulin resistance(IR) and serum proteins after radical gastrectomy. Twenty-two gastric cancer patients were randomly divided into the control (n=11) and intensive insulin therapy group (n=11), and underwent distal radical subtotal gastrectomy under epidural anesthesia. Fasting blood glucose (FBG), fasting insulin (FINS) and serum proteins were assayed preoperatively and at day 1, 3, 7 postoperatively. Insulin resistance index was calculated using homeostasis model assessment (HOMA). The length of hospital stay and postoperative complications were recorded respectively. (1)The levels of FBG, FINS, lnHOMA-IR (P<0.01,P<0.05) and the incidence of insulin resistance were remarkably decreased by intensive insulin therapy after the surgical procedure.(2)The levels of serum transferrin (TRF), prealbumin (PRE) and retinal binding protein (RBP) in the intensive insulin therapy group were significantly improved as compared to control group after operation(P<0.0