Details

Autor(en) / Beteiligte

• Vadlamudi, Raja S
• Van Dort, Martin
• Barklow, Thomas
• Byrd, Jr, Ryland P
• Moorman, Jonathan P

Titel

Strongyloides hyperinfection syndrome complicating (ectopic) Cushing syndrome

Ist Teil von

• Southern medical journal (Birmingham, Ala.), 2008-07, Vol.101 (7), p.750-752

Ort / Verlag

United States

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• Strongyloidiasis can present with a wide variety of symptoms and can lead to a potentially fatal hyperinfection. Although any factors that suppress the host defense mechanisms can potentially trigger hyperinfection, prolonged steroid use has been quite well described. A patient with disseminated small cell lung cancer suffered a Strongyloides stercoralis hyperinfection syndrome complicating ectopic adrenocorticotropic hormone (Cushing syndrome). Evaluation revealed lymphopenia, elevated levels of adrenocorticotropic hormone in the setting of elevated cortisol levels, a normal pituitary, and metastatic malignancy. S. stercoralis larval forms were seen in the stool and sputum. At autopsy, S. stercoralis larval forms were seen in the lung along with evidence of metastatic small cell lung carcinoma.