Details

Autor(en) / Beteiligte

• Snyderman, Selma E.
• Ketron, Katherine C.
• Carretero, Rosario
• Holt, L. Emmett

Titel

Site of Conversion of Tryptophan into Nicotinic Acid in Man.

Ist Teil von

• Experimental biology and medicine (Maywood, N.J.), 1949-04, Vol.70 (4), p.569-571

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

1949

Quelle

MEDLINE

Beschreibungen/Notizen

• Summary The intravenous administration of one gram of L-tryptophan to infants on constant diets gave a prompt and large rise in the urinary N1methyl nicotinamide which was equal in magnitude to that provoked by oral administration of the tryptophan. In view of these findings, the conversion of tryptophan to N1methyl nicotinamide in man seems to be mediated by the body tissues rather than by bacterial synthesis in the gastrointestinal tract.