Zhong yao cai, 2007-08, Vol.30 (8), p.989
2007
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- The role of apoptosis in herpes simplex virus I type myocarditis of mouse
- Ist Teil von
- Zhong yao cai, 2007-08, Vol.30 (8), p.989
- Ort / Verlag
- China
- Erscheinungsjahr
- 2007
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- To explore the relation among apoptosis of myocardial cell and the expression of TGF-beta1 in VMC. In the experiment, Viral myocarditis (VMC) in BALB/C mouse was obtained by inculating herpes simplex virus I type into abdominal cavity. The rate of VMC was 91.67% after 3 - 35 days of virus infection. The apoptosis (78.33%) and expression of TGF-beta1 (81.76%) were found in the myocardium of infected mouse by TUNEL and immunohistochemical method and electron microscope. AI of myocardial cell was 34.14+/-11.56 - 26.14+/-10.2. Apoptosis and expression of TGF-beta1 may participate in occurrence and development of VMC.
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 1001-4454Titel-ID: cdi_pubmed_primary_18074853
- Format
- –
- Schlagworte
- Animals, Apoptosis - physiology, Herpes Simplex - metabolism, Herpes Simplex - pathology, Herpes Simplex - virology, Immunohistochemistry, In Situ Nick-End Labeling, Male, Mice, Mice, Inbred BALB C, Microscopy, Electron, Myocarditis - metabolism, Myocarditis - pathology, Myocarditis - virology, Myocardium - metabolism, Myocardium - pathology, Myocardium - ultrastructure, Simplexvirus - physiology, Transforming Growth Factor beta - metabolism