Details

Autor(en) / Beteiligte

• Kang, I.H. (Sogang University, Seoul, Republic of Korea)
• Kim, J.S. (Sogang University, Seoul, Republic of Korea)
• Lee, J.K. (Sogang University, Seoul, Republic of Korea), E-mail: jgklee@sogang.ac.kr

Titel

The Virulence of Vibrio vulnificus is Affected by the Cellular Level of Superoxide Dismutase Activity

Ist Teil von

• Journal of microbiology and biotechnology, 2007-08, Vol.17 (8), p.1399-1402

Ort / Verlag

Seoul: Korean Society for Applied Microbiology

Erscheinungsjahr

2007

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The virulence of superoxide dismutase (SOD) mutants of Vibrio vulnificus, as tested by intraperitoneal injection into mice, decreases in the order of sodC mutant, sodA mutant, and sodB mutant lacking CuZnSOD, MnSOD, and FeSOD, respectively. The survival of SOD mutants under superoxide stress also decreases in the same order. The virulence of soxR mutant, which is unable to induce MnSOD in response to superoxide, is similar to that of the sodA mutant, as the survival of the soxR mutant under superoxide stress is similar to that of the sodA mutant.