Details

Autor(en) / Beteiligte

• Antinori, A
• Arendt, G
• Becker, J T
• Brew, B J
• Byrd, D A
• Cherner, M
• Clifford, D B
• Cinque, P
• Epstein, L G
• Goodkin, K
• Gisslen, M
• Grant, I
• Heaton, R K
• Joseph, J
• Marder, K
• Marra, C M
• McArthur, J C
• Nunn, M
• Price, R W
• Pulliam, L
• Robertson, K R
• Sacktor, N
• Valcour, V
• Wojna, V E

Titel

Updated research nosology for HIV-associated neurocognitive disorders

Ist Teil von

• Neurology, 2007-10, Vol.69 (18), p.1789-1799

Ort / Verlag

United States

Erscheinungsjahr

2007

Quelle

MEDLINE

Beschreibungen/Notizen

• In 1991, the AIDS Task Force of the American Academy of Neurology published nomenclature and research case definitions to guide the diagnosis of neurologic manifestations of HIV-1 infection. Now, 16 years later, the National Institute of Mental Health and the National Institute of Neurological Diseases and Stroke have charged a working group to critically review the adequacy and utility of these definitional criteria and to identify aspects that require updating. This report represents a majority view, and unanimity was not reached on all points. It reviews our collective experience with HIV-associated neurocognitive disorders (HAND), particularly since the advent of highly active antiretroviral treatment, and their definitional criteria; discusses the impact of comorbidities; and suggests inclusion of the term asymptomatic neurocognitive impairment to categorize individuals with subclinical impairment. An algorithm is proposed to assist in standardized diagnostic classification of HAND.