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Details

Autor(en) / Beteiligte
Titel
Study on the antiviral therapy program among people with human immunodeficiency virus in Guangxi Zhuang Authority
Ist Teil von
  • Zhōnghuá liúxíngbìng zázhì, 2007-04, Vol.28 (4), p.338
Ort / Verlag
China
Erscheinungsjahr
2007
Quelle
MEDLINE
Beschreibungen/Notizen
  • To explore the reconstitution of immune function and viral suppression condition and to analyze the occurrence of drug resistance HIV-1 variants and its prevalence after using HAART in Guangxi Autonomy Region. From July 2004 to October 2005, 133 HIV infected individuals who had received HAART for more than three months were recruited, and 58 infected persons with no antiviral therapy were selected as controls. Questionnaire was used to collect information about the adherence of HAART therapy. Immune reconstruction and viral suppress conditions were obtained by CD4+ counts and viral load and RT-PCR were used to amplify the PR and RT regions of HIV-1 genome while HIV-1 drug resistance rates were analyzed to show the occurrence and prevalence in both treated and naive patients. In terms of CD4+ T cell counts: 70.69% of the treated patients showed obvious increase and 23.28% had no apparent change but 6.03% of them went down. 70.48% of the patients who had received antiviral therapy more than 3 months had their v

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