Zhongguo xiu fu chong jian wai ke za zhi, 2007-05, Vol.21 (5), p.523
2007
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Details
- Autor(en) / Beteiligte
- Titel
- Study on collagen membrane combinating with autogenous bone marrow stromal cells or platelet rich plasma in repairing alveolar bone defect in dogs
- Ist Teil von
- Zhongguo xiu fu chong jian wai ke za zhi, 2007-05, Vol.21 (5), p.523
- Ort / Verlag
- China
- Erscheinungsjahr
- 2007
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- To evaluate the potential of bioresorbable collagen membrane in a combination with bone marrow stromal cells (BMSCs) or platelet rich plasma (PRP) in repairing alveolar bone defects. The first and second premolars were extracted from the bilateral maxillary and mandibular bone and four alveolar intrabone defects (8 mm in height, 5 mm in width, 15 mm in length) were created in 3 male mongrel dogs. The experiment included 4 groups: group A (nothing was used as control group), group B (only Bio-Gide), group C (Bio-Gide/ BMSCs) and group D (Bio-Gide/PRP). The macroscopic, radiographic and histological observations were performed at 4, 8 and 12 weeks after surgery. The cells were circle or short spindle-shape after 1 day of co-culture; and the cells were polygon and long spindle-shape with process after 3 days. The macroscopic observation: after 4 weeks in the defect region, obvious excavation and organization of hematoma were seen in group A; and new bone formation and little organization of hematoma were seen in
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 1002-1892Titel-ID: cdi_pubmed_primary_17578295
- Format
- –
- Schlagworte
- Alveolar Bone Loss - therapy, Animals, Biocompatible Materials, Bone Marrow Transplantation, Cell Differentiation, Cells, Cultured, Collagen, Disease Models, Animal, Dogs, Guided Tissue Regeneration - methods, Male, Osteogenesis, Platelet-Rich Plasma, Random Allocation, Stromal Cells - transplantation, Tissue Engineering, Transplantation, Autologous