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A study on the association of obstructive sleep apnea hypopnea syndrome with coronary atherosclerosis and coronary heart disease
Ist Teil von
Zhonghua jiehe he huxi zazhi, 2007-03, Vol.30 (3), p.178
Ort / Verlag
China
Erscheinungsjahr
2007
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
To investigate the association of obstructive sleep apnea hypopnea syndrome (OSAHS) with coronary atherosclerotic disease (CAD).
From March of 2005 to December of 2005, 82 subjects admitted into Department of Cardiology of The First Affiliated Hospital of Nanjing Medical University were recruited. They were divided into three groups based on their nocturnal apnea hypopnea index (AHI) detected by examination of polysomnography (PSG): mild OSAHS group (5 < AHI < or = 20, 38 cases), moderate-to-severe group (AHI > 20, 20 cases) and control group (AHI < 5, 24 cases). Coronary artery angiography and Gensini Score for assessing the severity of coronary atherosclerosis were performed in all three groups.
Compared with the control group, the apnea-hypopnea index (AHI) was significantly higher in OSAHS groups [10.9 (7.7 - 15.2), 29.3 (23.3 - 48.4) vs 2.9 (1.9 - 3.8)]. The minimal SpO(2) was significantly lower (84 +/- 9)%, (81 +/- 9)% in OSAHS groups than that in the control group (89 +/- 6)%. The incidence of CAD was