Details

Autor(en) / Beteiligte

• Chan-Yeung, M
• Ho, A S S
• Cheung, A H K
• Liu, R W T
• Yee, W K S
• Sin, K M
• Wong, M M L
• Lam, C W
• Chan, K S
• Lam, W K

Titel

Determinants of chronic obstructive pulmonary disease in Chinese patients in Hong Kong

Ist Teil von

• The international journal of tuberculosis and lung disease, 2007-05, Vol.11 (5), p.502

Ort / Verlag

France

Erscheinungsjahr

2007

Quelle

MEDLINE

Beschreibungen/Notizen

• The prevalence of chronic obstructive pulmonary disease (COPD) is rising in many parts of the world. This is a study of risk factors for COPD in Chinese patients in Hong Kong. Case-control study matched by sex and age (+/-5 years). A total of 289 consecutive patients with COPD were recruited from out-patient clinics while healthy controls were recruited from two sources: random population and community centres for senior citizens. All patients and controls underwent a questionnaire-based interview and spirometry. The mean ages of COPD patients and controls were 71.1 +/- 9.4 and 67.5 +/- 9.3 years, respectively. The male to female ratio of COPD patients was 5 to 1. Smoking was found to be the most important determinant for COPD, followed by poor education and low body mass index adjusted for confounders. A dose-dependent relationship was found between the risk of COPD and pack-years smoked. Place of birth, exposure to environmental tobacco smoke and a history of asthma and tuberculosis were not associated with increased risk of COPD. Despite a progressive reduction in prevalence, smoking remains the most important predictor of COPD in Hong Kong. Greater anti-smoking efforts are warranted.