AIDS research and human retroviruses, 2007-02, Vol.23 (2), p.335-340
2007
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Details
- Autor(en) / Beteiligte
- Titel
- Resistance mutations in subtype C HIV type 1 isolates from Indian patients of Mumbai receiving NRTIs plus NNRTIs and experiencing a treatment failure: resistance to AR
- Ist Teil von
- AIDS research and human retroviruses, 2007-02, Vol.23 (2), p.335-340
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2007
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We present here the first data available on resistance to nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) in India. In these subtype C isolates, we have observed most of the mutations noted in reverse transcriptase (RT) for subtype B with some additional substitutions (at positions 98, 203, 208, and 221) that will warrant attention in the algorithms used.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0889-2229eISSN: 1931-8405DOI: 10.1089/aid.2006.0183Titel-ID: cdi_pubmed_primary_17331042
- Format
- –
- Schlagworte
- Antiretroviral Therapy, Highly Active, Drug Resistance, Viral - genetics, HIV Infections - drug therapy, HIV Infections - genetics, HIV-1 - classification, HIV-1 - drug effects, HIV-1 - genetics, Humans, India, Mutation - genetics, Polymorphism, Genetic - genetics, Reverse Transcriptase Inhibitors - pharmacology, RNA-Directed DNA Polymerase - genetics, Treatment Failure