Details

Autor(en) / Beteiligte

• Luo, Dan
• Liu, Shu-yun
• Xing, Ai-yun

Titel

Expression and localization of estrogen receptor ERalpha and the kinds of ERbeta mRNA on placenta

Ist Teil von

• Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban, 2006-09, Vol.37 (5), p.769

Ort / Verlag

China

Erscheinungsjahr

2006

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the kinds of ERa, ERbeta mRNA and the localization of ERa, ERbeta on normal human placenta. The expression and localization of ERa,ERbeta on normal human placenta were detected by reverse transcription-ploymerase chain reaction (RT-PCR) and immunhistochemistry (SP-assay). There was mRNA expression of ERalpha and ERbeta on human term placenta, and ERbeta was identified with ERbeta5. The ERa immunoreactivity on human term placenta was in villous cytotrophoblastic nucleus, and that of ERbeta was in syncytiotrophoblastic cytoplasm. The findings indicate that ERbeta5 is the kind of ERbeta on placenta. It is localizated in the cytoplasm of syncytiotrophoblast and is probably connected with the production of estrogen.