La Presse médicale (1983), 2006-03, Vol.35 (3 Pt 1), p.421
2006
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Details
- Autor(en) / Beteiligte
- Titel
- Accelerated atheroma with prednisone and clopidogrel
- Ist Teil von
- La Presse médicale (1983), 2006-03, Vol.35 (3 Pt 1), p.421
- Ort / Verlag
- France
- Erscheinungsjahr
- 2006
- Quelle
- Elsevier ScienceDirect Journals
- Beschreibungen/Notizen
- Several mechanisms may explain the aggravation of atheroma lesions in patients receiving corticosteroid treatments. This 68-year-old man, a smoker with high cholesterol levels and a history of two transient ischemic attacks, also had severe Horton disease (giant cell arteritis) requiring treatment by corticosteroids and azathioprine. After a new transient ischemic accident, clopidogrel treatment was initiated. Ten months later, severe carotid stenosis was observed. Endarterectomy removed a recent thrombus and the pathology examination showed necrotic lesions complicated by hemorrhage with inflammatory infiltrate. This patient's atheromatous disease was aggravated by intraplaque hemorrhage, caused by several factors include his corticosteroid therapy and platelet aggregation inhibition treatment.
- Sprache
- Französisch
- Identifikatoren
- ISSN: 0755-4982DOI: 10.1016/S0755-4982(06)74607-3Titel-ID: cdi_pubmed_primary_16550133
- Format
- –
- Schlagworte
- Aged, Atherosclerosis - chemically induced, Atherosclerosis - pathology, Carotid Stenosis - diagnosis, Carotid Stenosis - pathology, Carotid Stenosis - surgery, Endarterectomy, Giant Cell Arteritis - drug therapy, Glucocorticoids - adverse effects, Glucocorticoids - therapeutic use, Humans, Inflammation, Male, Necrosis, Platelet Aggregation Inhibitors - adverse effects, Platelet Aggregation Inhibitors - therapeutic use, Prednisone - adverse effects, Prednisone - therapeutic use, Ticlopidine - adverse effects, Ticlopidine - analogs & derivatives, Ticlopidine - therapeutic use