Neurology, 2005-08, Vol.65 (3), p.444-447
2005
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- Autor(en) / Beteiligte
- Titel
- A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster
- Ist Teil von
- Neurology, 2005-08, Vol.65 (3), p.444-447
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2005
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-3878eISSN: 1526-632XDOI: 10.1212/01.WNL.0000168259.94991.8aTitel-ID: cdi_pubmed_primary_16087911
- Format
- –
- Schlagworte
- Acute Disease - therapy, Adult, Aged, Aged, 80 and over, Amines - administration & dosage, Amines - therapeutic use, Analgesics - administration & dosage, Analgesics - therapeutic use, Anticonvulsants - administration & dosage, Anticonvulsants - therapeutic use, Cross-Over Studies, Cyclohexanecarboxylic Acids - administration & dosage, Cyclohexanecarboxylic Acids - therapeutic use, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Female, gamma-Aminobutyric Acid - administration & dosage, gamma-Aminobutyric Acid - therapeutic use, Herpes Zoster - complications, Herpes Zoster - physiopathology, Humans, Hyperalgesia - drug therapy, Hyperalgesia - etiology, Hyperalgesia - physiopathology, Male, Middle Aged, Pain Measurement, Pain Threshold - drug effects, Pain Threshold - physiology, Treatment Outcome