Zhōnghuá zhŏngliú zázhì, 2005-05, Vol.27 (5), p.286
2005
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- Autor(en) / Beteiligte
- Titel
- Detection and clinical study of serum tumor markers in patients with colorectal cancer
- Ist Teil von
- Zhōnghuá zhŏngliú zázhì, 2005-05, Vol.27 (5), p.286
- Ort / Verlag
- China
- Erscheinungsjahr
- 2005
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- To investigate the diagnostic value and clinical significance of serum tumor markers CEA, CA19-9 and CA242 in patients with colorectal cancer. The serum levels of CEA, CA19-9 and CA242 were determined by ELISA before surgery in 134 patients with colorectal cancer and in 200 healthy people as a control. The CEA, CA19-9 and CA242 levels in patients were significantly higher than those in controls (P < 0.01, respectively). The sensitivity of CEA and CA242 for colorectal cancer diagnosis was higher than that of CA19-9, and the combined sensitivity of CEA + CA242 and CEA + CA242 + CA19-9 were higher than that of single item or the other two combinations (CEA + CA19-9 and CA19-9 + CA242). In Dukes stages A, B, C and D, serum levels and sensitivity of the three tumor markers were significantly and successively increased. In the cases with lymph node metastasis, levels of the three tumor markers were significantly increased. The markers levels were also significantly and successively increased along with the extent o
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 0253-3766Titel-ID: cdi_pubmed_primary_15996321
- Format
- –
- Schlagworte
- Adult, Aged, Antigens, Tumor-Associated, Carbohydrate - blood, Biomarkers, Tumor - blood, CA-19-9 Antigen - blood, Carcinoembryonic Antigen - blood, Colorectal Neoplasms - diagnosis, Colorectal Neoplasms - pathology, Female, Humans, Lymph Nodes - pathology, Lymphatic Metastasis, Male, Middle Aged, Neoplasm Invasiveness, Sensitivity and Specificity