Details

Autor(en) / Beteiligte

• Schortinghuis, Jurjen
• Ruben, Jan L
• Raghoebar, Gerry M
• Stegenga, Boudewijn
• de Bont, Lambert G M

Titel

Does ultrasound stimulate osteoconduction? A placebo-controlled single-blind study using collagen membranes in the rat mandible

Ist Teil von

• The International journal of oral and maxillofacial implants, 2005-03, Vol.20 (2), p.181

Ort / Verlag

United States

Erscheinungsjahr

2005

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate whether ultrasound can stimulate osteoconduction in the mandible, an attempt was made to stimulate the osteoconductive process with low-intensity pulsed ultrasound in rats. In 64 rats, a 5.0-mm diameter circular mandibular defect was made in the ramus and, subsequently, covered on both sides with collagen membranes. Two groups were studied, an ultrasound treatment group and a placebo treatment group. At 2 and 4 weeks, the remaining defect area was measured using microradiographs, and the amount of osteoconduction was expressed as the percentage of defect closure. At 2 and 4 weeks, there was no significant difference in the percentage of defect closure between the groups. An explanation may be that ultrasound does not exert an effect in an area where wound healing is already expected to be at an optimal level. There was no evidence that low-intensity pulsed ultrasound stimulates osteoconduction in a bone defect in the rat mandible that is covered by a collagen membrane.