Details

Autor(en) / Beteiligte

• Lu, Shu-Liang
• Liao, Zhen-Jiang
• Xiang, Jun
• Wang, Zhi-Yong
• Yang, Li-Ying
• Jin, Shu-Wen
• Shi, Ji-Xiang

Titel

Influence of tangential excision within 24 postburn hours on the local wound inflammatory response in patients with deep partial thickness burn

Ist Teil von

• Zhonghua shao shang za zhi, 2005-02, Vol.21 (1), p.24

Ort / Verlag

China

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the influence of early tangential excision within 24 postburn hours on local wound inflammatory response and tissue injury in patients with deep partial thickness burn. Twelve patients with deep partial thickness burn were enrolled in the study. Tangential excision was performed within 24 postburn hours. The same wound of a patient was divided into three areas for harvesting tissue samples, i.e. pre-operation, post-operation and non-operation areas. For each patient, the biopsies from the pre-operation area were harvested before tangential excision, while those from post-operation and non-operation areas were harvested during 5 to 7 postburn days (PBDs). The contents of IL-8, MPO and MDA in wound tissue were determined by tissue culture and chemical colorimetry, respectively. HE and Mason's staining were employed to assess the degree of necrosis of the wound tissue. The IL-8, MPO and MDA contents in the local wound tissue after tangential excision were 6.83 +/- 1.85 microg/L, 4.07 +/- 0.87 U/g,