Details

Autor(en) / Beteiligte

• Morioka, Takato
• Hashiguchi, Kimiaki
• Fukui, Kimiko
• Kawamura, Tadao
• Sasaki, Masayuki
• Mihara, Futoshi
• Sasaki, Tomio

Titel

Surgical treatment for temporal lobe epilepsy in patients over age 50 years

Ist Teil von

• No To Shinkei, 2004-04, Vol.56 (4), p.326

Ort / Verlag

Japan

Erscheinungsjahr

2004

Quelle

MEDLINE

Beschreibungen/Notizen

• We retrospectively analyzed 4 patients over age 50 (52 - 57) years with intractable medial temporal lobe epilepsy(MTLE) who underwent the anterior temporal lobectomy with hippocampectomy. Case 1 had MTLE with old brain abscess in the left lateral temporal lobe and Cases 2 - 4 had MTLE with histologically verified hippocampal sclerosis. In Cases 2 - 4, although the onset of seizures occurred 26 to 37 years prior to the time of surgery, there was no mental problem (IQ = 87 - 100). In Cases 1, chronic invasive electrocorticography recording using subdural electrodes was obtained, while in Case 2 - 4, the epileptogenic region was defined by noninvasive preoperative evaluation. Postoperatively, all patients obtained a meaningful improvement, becoming either free from seizures or only experiencing a rare seizure, and returned to work or usual activities without surgical complications. Surgery for MTLE appears to be effective for older individuals and carries a small risk of postoperative complications.