Details

Autor(en) / Beteiligte

• Xu, Cai-gang
• Zhu, Huan-ling
• Wu, Tai-xiang
• Wu, Yu
• Zheng, Su-ping
• Wu, Jin-xu

Titel

A paired case-control study for assessing the relationship between the incidence of malignant lymphomas and the viruses infections

Ist Teil von

• Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban, 2004-03, Vol.35 (2), p.247

Ort / Verlag

China

Erscheinungsjahr

2004

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• To evaluate the relationships between the viruses infections and the incidence of malignant lymphomas (ML) in Sichuan province. A hospital-based paired case-control study was designed with two controls per case. The case group comprised 97 cases diagnosed as ML by pathological examination; the control group A consisted of 194 subjects randomly selected from those with non-malignancies by matching on both gender and age in the corresponding period. Additionally, a control group B for Epstein-Barr virus(EBV), including 80 subjects, were chosen from other non-malignant diseases at the same time. Enzyme-linked immunosorbent assay(ELISA) was employed to test the serum antibodies and antigens of hepatitis C virus (HCV), human immunodeficiency virus (HIV), cytomegalovirus (CMV), and hepatitis B virus (HBV). The EBV was confirmed by the EBER in situ-hybridization (EBER-ISH) of pathological tissue. The positive rate of EBV in ML group was 70.1%(68/97) and that of control group was 7.5%(6/80). The difference between th