Details

Autor(en) / Beteiligte

• Guo, Xiang-yang
• Yi, Jie
• Yie, Tie-hu
• Luo, Ai-lun
• Ren, Hong-zhi
• Huang, Yu-guang

Titel

Remifentanil for intraoperative anesthesia

Ist Teil von

• Zhōngguó yīxué kēxuéyuàn xuébào, 2004-02, Vol.26 (1), p.66

Ort / Verlag

China

Erscheinungsjahr

2004

Quelle

MEDLINE

Beschreibungen/Notizen

• To compare the efficacy and safety of remifentanil with fentanyl used for intraoperative anesthesia. Fifty-four patients undergoing modified radical mastectomy or total hysterectomy were randomly assigned to remifentanil group or fentanyl group with 27 cases in each group. Anesthesia was induced with propofol (2 mg/kg) and either remifentanil (2 micrograms/kg) or fentanyl (2.5 micrograms/kg), and was maintained with inhalation of nitrous oxide in oxygen (2:1) and a continuous infusion of either remifentanil (0.2 microgram.kg-1.min-1) or fentanyl (0.03 microgram.kg-1.min-1). Depth of anesthesia, hemodynamic changes, recovery profile of anesthesia, postoperative analgesia and adverse reactions were observed. The number of patients exhibited light depth of anesthesia during tracheal intubation and maintenance in the remifentanil group was significantly fewer than that in the fentanyl group (P < 0.05). Hemodynamic changes during intubation, skin incision, maintenance of anesthesia and extubation in the remifentan