Details

Autor(en) / Beteiligte

• Gao, Xiang-wei
• Xu, Zheng-ping
• Huo, Ya-nan
• Jiang, Huai
• Fu, Yi-ti
• Lu, De-qiang
• Zeng, Qun-li

Titel

Noise magnetic fields block co-suppression effect induced by power frequency magnetic field and phorbol ester

Ist Teil von

• Zhōnghuá yùfáng-yīxué zázhì, 2004-01, Vol.38 (1), p.11

Ort / Verlag

China

Erscheinungsjahr

2004

Quelle

MEDLINE

Beschreibungen/Notizen

• To explore intervention with electromagnetic noise for co-suppression effect on gap-junctional intercellular communication (GJIC) induced or strengthened by low intensity magnetic field with carcinogen 12-O-tetradecanoylphorbol-13-acetate (TPA). Fibroblast cells from NIH 3T3 mice were exposed to extremely low intensity magnetic field (MF) 0.2 mT, 0.2 mT + TPA or/and electromagnetic noise with the same intensity of MF for 24 h, and GJIC was determined using fluorescence recovery analysis after photobleaching (FRAP) with a laser-scanning confocal microscope (Leica, Germany). GJIC function could be co-suppressed by MF of 0.2 mT with TPA, with fluorescence recovery of (23 +/- 11)%, lower than that in the control group [(46 +/- 19)%] and in the group with TPA only [(34 +/- 17) %] (P < 0.01), indicating 0.2 mT MF plus TPA could co-inhibit GJIC (P < 0.01). Superposition of 0.2 mT noise MF could get a fluorescence recovery of (35 +/- 19)% and significantly antagonize its co-suppression by TPA. Electromagnetic noise o