Details

Autor(en) / Beteiligte

• Mehltretter, C.L.

Titel

The Chemical Synthesis of D-Glucuronic Acid

Ist Teil von

• Advances in Carbohydrate Chemistry, 1953, Vol.8, p.231-249

Ort / Verlag

United States: Elsevier Science & Technology

Erscheinungsjahr

1953

Quelle

MEDLINE

Beschreibungen/Notizen

• The methods for preparing D-glucuronic acid is devised through the oxidation of derivatives of D-glucose by halogens, hydrogen peroxide, and potassium permanganate. In some of these reactions, only the aldehyde function of D-glucose is protected from oxidation, and in others the secondary hydroxyl groups also are blocked. After removal of barium with sulfuric acid, the aqueous solution of D-glucuronic acid is evaporated in vacuo to a sirup, which crystallized upon seeding with authentic D-glucuronolactone. Derivatives of D-glucose in which all the secondary hydroxyl groups are not blocked, have been used chiefly in attempts to devise an economical process for the large-scale manufacture of D-glucuronic acid. The chapter reports methods for producing D-glucuronic acid by alkaline permanganate oxidation of soluble starch, and of D-glucose derivatives in which the aldehyde function is protected.