Details

Autor(en) / Beteiligte

• Iakushin, S S
• Okorokov, V G
• Liferov, R A
• Fomina, V A
• Ivanova, G O

Titel

Assessment of safety and antihypertensive efficacy of a cardioselective beta-blocker nebivolol in patients with hypertension and concomitant chronic obstructive bronchitis

Ist Teil von

• Kardiologiia, 2002, Vol.42 (11), p.36

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

2002

Quelle

MEDLINE

Beschreibungen/Notizen

• Safety, tolerability and antihypertensive efficacy of a cardioselective beta-blocker nebivolol was studied in 30 patients with mild and moderate hypertension and concomitant stage I chronic obstructive bronchitis. Nebivolol (5 mg/day) was given for 1 month; in 5 patients complementary hydrochlorothiazide (12.5 mg/day) was required for sufficient antihypertensive effect. Nebivolol was well tolerated (only 1 patient complained of head ache), did not cause worsening of bronchitis and spirometric parameters, exerted no cardiodepressive action, and did not induce apparent disturbances of metabolism.