Endocrinology and Metabolism Clinics of North America, 2002-06, Vol.31 (2), p.295-320
2002
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- APS-I/APECED: the clinical disease and therapy
- Ist Teil von
- Endocrinology and Metabolism Clinics of North America, 2002-06, Vol.31 (2), p.295-320
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 2002
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The clinical picture and course of APS-I or APD-I/APECED is widely variable: the list of possible disease components includes some 30 disorders. The initial manifestation may not include any of the known characteristic components, namely, mucocutaneous candidiasis, hypoparathyroidism, or adrenocortical insufficiency. Although mutation detection is available, it does not help to exclude this disease. Diagnostic strategy needs to be based on knowledge of the clinical picture, including the features of ectodermal dystrophy.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0889-8529eISSN: 1558-4410DOI: 10.1016/S0889-8529(01)00013-5Titel-ID: cdi_pubmed_primary_12092452
- Format
- –
- Schlagworte
- Adolescent, Adult, Candidiasis, Chronic Mucocutaneous - diagnosis, Candidiasis, Chronic Mucocutaneous - genetics, Candidiasis, Chronic Mucocutaneous - therapy, Child, Chromosomes, Human, Pair 21, Female, Finland, Humans, Immunosuppressive Agents - therapeutic use, Male, Middle Aged, Mouth Diseases - microbiology, Mutation, Polyendocrinopathies, Autoimmune - complications, Polyendocrinopathies, Autoimmune - diagnosis, Polyendocrinopathies, Autoimmune - genetics, Polyendocrinopathies, Autoimmune - therapy, Prognosis