Details

Autor(en) / Beteiligte

• Tada, Atsuhiko
• Ueoka, Hiroshi
• Kiura, Katsuyuki
• Tabata, Masahiro
• Takemoto, Mitsuhiro
• Yamane, Hiromichi
• Hiyama, Junichiro
• Aoe, Keisuke
• Shibayama, Takuo
• Kamei, Haruhito
• Kawahara, Shin
• Harita, Shingo
• Sato, Toshio
• Kobayashi, Makoto
• Eguchi, Kenji
• Hiraki, Shunkichi
• Hiraki, Yoshio
• Tanimoto, Mitsune

Titel

Combination chemotherapy with carboplatin and etoposide for elderly patients aged 76 years or older with small cell lung cancer

Ist Teil von

• Gan to kagaku ryoho, 2002-05, Vol.29 (5), p.751

Ort / Verlag

Japan

Erscheinungsjahr

2002

Quelle

MEDLINE

Beschreibungen/Notizen

• Eighteen elderly patients aged 76 years or older with small cell lung cancer were treated with carboplatin (AUC = 4 mg/ml.min, i.v. day 1) and etoposide (70 mg/m2 i.v. day 1-3) and 17 patients were evaluable. The median age of the study population was 77 years (range: 76-81). Eight patients had limited disease (LD) and nine did extensive disease (ED). The overall response rate was 88% for LD patients and 67% for ED patients. Median survival time was 219 days for LD patients and 158 days for ED patients. Grade 3 and 4 leukopenia, neutropenia, thrombocytopenia and anemia occurred in 41%, 76%, 24% and 6% of patients, respectively. There was one treatment-related death due to pneumonitis.