Details

Autor(en) / Beteiligte

• Koennecke, H C
• Leistner, S

Titel

Prophylactic antipyretic treatment with acetaminophen in acute ischemic stroke: a pilot study

Ist Teil von

• Neurology, 2001-12, Vol.57 (12), p.2301-2303

Ort / Verlag

United States

Erscheinungsjahr

2001

Quelle

MEDLINE

Beschreibungen/Notizen

• Fever is associated with poor outcome in acute stroke. Forty-two consecutive, normothermic patients with acute ischemic stroke were, within 24 hours from symptom onset, randomized to either receive 4 g acetaminophen daily (n = 20) or matched placebo (n = 22). Fever of greater than 37.5 degrees C occurred in 36.4% of patients in the placebo group, compared with 5.0% in the acetaminophen group (Fisher's exact test, p = 0.014). Prophylactic antipyretic treatment with acetaminophen may be effective in the prevention of fever after acute ischemic stroke.