Details

Autor(en) / Beteiligte

• Ben Halima, M
• Pasquier, C
• Slim, A
• Ben Chaabane, T
• Arrouji, Z
• Puel, J
• Ben Redjeb, S
• Izopet, J

Titel

First molecular characterization of HIV-1 Tunisian strains

Ist Teil von

• Journal of acquired immune deficiency syndromes (1999), 2001-09, Vol.28 (1), p.94-96

Ort / Verlag

United States

Erscheinungsjahr

2001

Quelle

MEDLINE

Beschreibungen/Notizen

• In order to identify HIV-1 subtypes circulating in Tunisia, blood specimens from 25 HIV-1 infected Tunisian patients were collected. Proviral HIV-1 DNA was genotyped by sequence analysis of the C2-V3 env region. HIV-1 subtypes were determined in 21 DNA sequences: 20 were of subtype B and one was a circulating recombinant form (CRF02 AG). Subtype B largely dominates the epidemiology of HIV-1 infection in Tunisia, suggesting the probable imported origin of HIV-1 infection, but further studies are needed to investigate the potential diversification of HIV-1 isolates in Tunisia.