Details

Autor(en) / Beteiligte

• Osawa, H
• Aiba, K
• Uno, S
• Hanai, M
• Yamada, Y
• Takahashi, S
• Ito, Y
• Horikoshi, N

Titel

Multi-drug resistant breast cancer responding to chemotherapy with docetaxel (taxotere: TXT)

Ist Teil von

• Gan to kagaku ryoho, 1999-08, Vol.26 (9), p.1329

Ort / Verlag

Japan

Erscheinungsjahr

1999

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The patient was a fifty-five year old female who had stage IVb advanced breast cancer with hypoxia due to bilateral pulmonary metastases and lymphangitis. The cancer was adriamycin (ADM) and multi-drug resistant. We administered docetaxel (taxotere: TXT) 60 mg/m2 every 3 weeks. After 2 courses, the pulmonary metastases had become remarkably reduced in size and hypoxia was reduced and performance status (PS) improved. Major toxic defects were grade-4 neutropenia and hair loss. The patient could be discharged from the hospital without O2 inhalation and enjoyed a better quality of life (QOL). This chemotherapy is thought to be effective against ADM and multi-drug resistant breast cancer.