Details

Autor(en) / Beteiligte

• Kerr, Daniel J
• Miletic, Michael
• Chaplin, Jason H
• White, Jonathan M
• Flynn, Bernard L

Titel

Oxazolidinone-Promoted, Torquoselective Nazarov Cyclizations

Ist Teil von

• Organic letters, 2012-04, Vol.14 (7), p.1732-1735

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Oxazolidinones are powerful promoters of the Nazarov reaction, enabling the cyclization of conventionally resistant substrates to be achieved under mild conditions. They exert excellent regio- and torquoselective control in both the conventional Nazarov reaction giving cyclopentenones and in the “interrupted” Nazarov reaction, giving more highly substituted multistereocenter containing products.