Details

Autor(en) / Beteiligte

• Lawson, Nathan D.
• Wolfe, Scot A.

Titel

Forward and Reverse Genetic Approaches for the Analysis of Vertebrate Development in the Zebrafish

Ist Teil von

• Developmental cell, 2011-07, Vol.21 (1), p.48-64

Ort / Verlag

Cambridge, MA: Elsevier Inc

Erscheinungsjahr

2011

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The development of facile forward and reverse genetic approaches has propelled the deconvolution of gene function in biology. While the origins of these techniques reside in the study of single-cell or invertebrate organisms, in many cases these approaches have been applied to vertebrate model systems to gain powerful insights into gene function during embryonic development. This perspective provides a summary of the major forward and reverse genetic approaches that have contributed to the study of vertebrate gene function in zebrafish, which has become an established model for the study of animal development.