Details

Autor(en) / Beteiligte

• Bhuchar, Neha
• Deng, Zhicheng
• Ishihara, Kazuhiko
• Narain, Ravin

Titel

Detailed study of the reversible addition–fragmentation chain transfer polymerization and co-polymerization of 2-methacryloyloxyethyl phosphorylcholine

Ist Teil von

• Polymer chemistry, 2011, Vol.2 (3), p.632-639

Erscheinungsjahr

2011

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In this paper, we report on a detailed study of the reversible addition-fragmentation chain transfer (RAFT) polymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC). The RAFT polymerization conditions were carefully monitored and it was noted that well-defined homopolymers with ideal low polydispersity (Mw/Mn 1.2) could be achieved in methanol using 4-cyanopentanoic acid dithiobenzoate (CTP) as a chain transfer agent and 4,4[prime or minute]-azobis(4-cyanovaleric acid) (ACVA) as an initiator. A series of well-defined block copolymers having a range of compositions and molecular weight were prepared using poly(MPC) as the macroCTA. Statistical MPC-based copolymers of biological relevance were also synthesized and characterized.