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Complex Mammary Adenoma with Sebaceous Differentiation in a Dog
Ist Teil von
Journal of comparative pathology, 2012-02, Vol.146 (2-3), p.165-167
Ort / Verlag
England: Elsevier Ltd
Erscheinungsjahr
2012
Quelle
MEDLINE
Beschreibungen/Notizen
Sebaceous metaplasia arising within a complex adenoma of the left fourth mammary gland is described in a 9-year-old miniature pinscher bitch. Microscopically, the tumour was composed of tubular and ductular structures admixed with clusters of spindle-shaped, myoepithelial-like cells and units formed of well-differentiated sebocytes surrounded by basaloid cells. Abundant lipid droplets were identified within the latter population by Sudan III staining. Immunohistochemical expression of cytokeratin AE1/AE3 was detected in epithelial cells and in the cells with sebaceous differentiation.