Details

Autor(en) / Beteiligte

• Cho, Eun Byul
• Park, Hoon
• Park, Eun Joo
• Kwon, In Ho
• Kim, Sang Seok
• Kim, Kwang Ho
• Kim, Kwang Joong
• Park, Hye Rim

Titel

Effect of Intense Pulsed Light on Rat Skin

Ist Teil von

• Dermatologic surgery, 2012-03, Vol.38 (3), p.430-436

Ort / Verlag

Malden, MA: Wiley

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Intense pulsed light (IPL) is widely used in treating skin conditions and has been reported to increase collagen and elastic fibers without damaging the epidermis. Objective To evaluate the effect of variation in the number of passes and intervals of IPL treatments on photorejuvenation in rats. Materials and Methods Groups of two rats each were exposed to two or four passes of an IPL source using a fluence of 30 J/cm2 and a cut‐off filter of 560 nm at 1‐ or 3‐week intervals. The collagen and elastic fiber content in stained tissue biopsies and the thickness of the collagen fibers of IPL‐irradiated and unexposed skin regions were compared. Results Collagen distribution and collagen fiber diameter was in IPL‐irradiated than in control regions. The number of passes did not significantly affect the collagen fiber thickness, but the collagen fibers from the 3‐week‐interval groups were thicker than those of the 1‐week‐interval groups (p < .001). Conclusion IPL increased dermal collagen fibers and collagen fiber diameter, suggesting efficacy in photorejuvenation and wrinkle reduction.