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Details

Autor(en) / Beteiligte
Titel
Role of Spinal Cord in Regulating Mouse Kidney: A Virally Mediated Trans-synaptic Tracing Study
Ist Teil von
  • Urology (Ridgewood, N.J.), 2012-03, Vol.79 (3), p.745.e1-745.e4
Ort / Verlag
United States: Elsevier Inc
Erscheinungsjahr
2012
Quelle
MEDLINE
Beschreibungen/Notizen
  • Objective To determine the spinal innervation and neuronal connections is important for studying renal metabolic responses. Materials and Methods In this study, the spinal cords of 10 adult male C57BL/6J strain mice were mapped retrograde using injections of pseudorabies virus (PRV)-614. The virus, injected into the kidney, was specifically transported to the spinal cord. Results At 5 days after injection of the PRV-614, PRV-614–positive cells were found in the intermediolateral cell column, the intercalates nucleus, or the central autonomic nucleus of spinal cord segments T4-L1, and most PRV-614–labeled cells were found in the T9 segment. Conclusion Our results revealed neuroanatomical circuits between kidney and the spinal intermediolateral cell column neurons.

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