Details

Autor(en) / Beteiligte

• Khokha, Mustafa K.

Titel

Xenopus white papers and resources: Folding functional genomics and genetics into the frog

Ist Teil von

• Genesis (New York, N.Y. : 2000), 2012-03, Vol.50 (3), p.133-142

Ort / Verlag

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

Erscheinungsjahr

2012

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• The frog Xenopus has been vital for biomedical science for over 80 years, contributing to diverse fields from cell signaling, cell and developmental biology, to ion channel physiology and toxicology. Its experimentally manipulable oocytes and embryos provide abundant material for molecular and biochemical approaches for a wide range of gene discovery and protein function studies. In recent years, the Xenopus community has invested in key resources for functional genomics, including genome‐wide full‐length cDNA collections and genome assemblies as well as genetic tools. These assets combine with Xenopus' extensive range of functional assays to create exciting new research avenues with medical as well as basic applications. This review describes how these resources were developed and what new tools are on the horizon. genesis 50:133–142, 2012. © 2012 Wiley Periodicals, Inc.