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Details

Autor(en) / Beteiligte
Titel
Colonoscopy versus Fecal Immunochemical Testing in Colorectal-Cancer Screening
Ist Teil von
  • The New England journal of medicine, 2012-02, Vol.366 (8), p.697-706
Ort / Verlag
United States: Massachusetts Medical Society
Erscheinungsjahr
2012
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
  • This trial comparing colorectal-cancer mortality among patients screened with colonoscopy or fecal immunochemical testing (FIT) will be completed in 2021. As compared with FIT, colonoscopy detected a similar number of cancers but more adenomas on baseline screening. Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related deaths. 1 Several studies have shown that colorectal-cancer screening is effective 2 – 5 and cost-effective 6 in the average-risk population. Recommended strategies for colorectal-cancer screening fall into two broad categories: stool tests (occult blood and exfoliated DNA tests) and structural examinations (flexible sigmoidoscopy, colonoscopy, and computed tomographic colonography). Stool tests primarily detect cancer, and structural examinations detect both cancer and premalignant lesions. 2 Stool tests for occult blood (guaiac testing and fecal immunochemical testing [FIT]) are predominantly used in Europe and Australia, whereas colonoscopy is the predominant screening . . .

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