Angewandte Chemie (International ed.), 2012-02, Vol.51 (7), p.1706-1709
International ed. in English, 2012
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Details
- Autor(en) / Beteiligte
- Titel
- Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin
- Ist Teil von
- Angewandte Chemie (International ed.), 2012-02, Vol.51 (7), p.1706-1709
- Auflage
- International ed. in English
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2012
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Malaria is a serious global health issue. Artemisinin combination treatments are the first‐line drugs, but supplies are limited because artemisinin is obtained solely by extraction from Artemisia annua. A continuous‐flow process that converts dihydroartemisinic acid into artemisinin (see scheme) was shown to be an inexpensive and scalable process that can ensure a steady, affordable supply of artemisinin.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1433-7851eISSN: 1521-3773DOI: 10.1002/anie.201107446Titel-ID: cdi_proquest_miscellaneous_920365302
- Format
- –
- Schlagworte
- Antimalarials - chemical synthesis, Antimalarials - chemistry, Artemisia annua, artemisinin, Artemisinins - chemical synthesis, Artemisinins - chemistry, Chromatography, High Pressure Liquid - instrumentation, drug research, Drugs, Extraction, flow chemistry, Health, Malaria, Molecular Conformation, photochemistry, Photochemistry - instrumentation, Synthesis